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up in some places (for now). Here’s why When it comes to anaphylaxis — or severe allergic reactions — “the rate is now around two to five per million,” Hotez said. That means about 0.0005% (or less) of those who get a Covid-19 vaccine have a serious, negative response. These are the symptoms of anaphylaxis The good news is even when severe outcomes do happen, “they usually happen in the first 30 minutes,” Hotez said. “That’s why vaccine sites keep people there for 15 to 30 minutes afterward — to make certain they’re not having an anaphylactic reaction.” The CDC recommends people who have had a severe allergic reaction to a different vaccine or a history of anaphylaxis stay for 30 minutes after vaccination. Others could leave after 15 minutes. All places administering vaccines must be armed with epinephrine to quickly combat any cases of anaphylaxis, the CDC said. Do some vaccines produce more side effects than others? Every body is different. So the exact same vaccine can leave one person feeling sick for a day and another person feeling perfectly fine. With that said, “the mRNA vaccines — the Pfizer and the Moderna — they are what’s called more reactogenic, meaning there are more side effects,” Hotez said. Pfizer/BioNTech says its Covid-19 vaccine is 100% effective and well tolerated in adolescents “They’re not serious side effects, but they can be unpleasant, and they can sometimes last a day or two. Usually they don’t. Usually they last a few hours.” Both the Pfizer/BioNTech and Moderna vaccines give about 95% protection against symptomatic Covid-19, and both are virtually 100% effective against severe Covid-19 illness. In their clinical

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