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time,” said Dr. Anne Schuchat, principal deputy director of the CDC. “For people who recently got the vaccine within the last couple of weeks, they should be aware to look for symptoms. If you received the vaccine and develop severe headaches, abdominal pain, leg pain or shortness of breath, you should contact your health care provider.” What to make of the J&J vaccine pause? A doctor who got the shot herself says she’s not worried The Johnson & Johnson vaccine uses a completely different technology than the Pfizer/BioNTech and Moderna mRNA vaccines. Johnson & Johnson’s is an adenovirus vector vaccine, which “may have something to do with” the reported blood clots, said Dr. Carlos del Rio, executive associate dean of the Emory University School of Medicine. Many sites that were giving the single-dose Johnson & Johnson vaccine are giving the Pfizer/BioNTech or Moderna vaccines instead. Is it true second doses are worse than the first? Both the Pfizer/BioNTech and Moderna vaccines require two doses. It’s true that some people have reported stronger side effects after their second doses, according to both Pfizer and Moderna. But again, that’s another sign the vaccines are doing what they’re supposed to. Why that 2nd dose of vaccine can be a doozy “With the first dose, you are having to generate an immune response from the ground up,” said Michael Worobey, an evolutionary biology professor at the University of Arizona. The body produces antibodies, but also starts to generate immune cells called B cells to make targeted antibodies — and that takes time, Worobey said. “Then the second time you give a person the shot, those cells are sitting around like a clone army and can immediately start producing a very big immune response, which is what is happening when people feel like they

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